Action of Enzyme food, green life enzyme on systemic and local anaphylaxis > Volume 03 - 2003

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Oriental Pharmacy and Experimental Medicine
Volume 03 - 2003
Date: 2003

Journal: Pages 46-50

Fevruary 2003 | Action of Enzyme food, green life enzyme on systemic and local anaphylaxis…

Phil-Dong Moon1, Ho-Jeong Na1 and Hyung-Min Kim1,*

첨부파일

Summary

​We studied the inhibitory effect of Green Life Enzyme (GLE) on compound 48/80-induced anaphylacticresponse in a murine model. GLE inhibited compound 48/80-induced systemic anaphylacticshock at the dose of 10g/kg by 87.5%. When GLE was given as pre-treatment at concentrationsranging from 0.01 to 1.0g/kg, it inhibited passive cutaneous anaphylaxis activated by anti-dinitrophenyl (DNP) IgE. In addition, GLE (0.1mg/ml) inhibited anti-DNP IgE-induced tumor necrosisfactor-a production from mast cells by 69% compared to saline value. These results indicate that GLEmay possess anti-anaphylactic and anti-inflammatory activity.


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