Ginseng root has been used as a tonic remedy in Traditional Chinese Medicine for centuries.Modern studies have demonstrated that ginseng root has complex components and multiplepharmacological properties. The effects of ginseng leaf, however, are not well known. Recentstudies show that compared to ginseng root, ginseng leaf and stem exhibit a higher content ofactive compositions such as ginsenosides, polysaccharides, triterpene flavonoids, volatile oil,polyacetylenic alcohols, peptides, amino acids and fatty acids. Ginseng leaf possesses multiplepharmacological effects in the central nervous, cardiovascular, growth and metabolism systems.Additionally, the leaf has anti-fatigue, anti-hyperglycemic, anti-oxidant, and anti-aged effects. Ingeneral, ginseng leaf is quite safe, but adverse effects may occur if it is abused or is of poor quality.Thus, attention must be paid to dosages, quality, and standardization of ginseng leaf products.