The crude methanolic extract of the leaves of Amoora cucullata Roxb. was investigated for itspossible anti-inflammatory activity using carrageenin induced rat paw edema model and cottonpellet implantation method in rat. The extract was also studied for its antinociceptive activityusing acetic acid induced writhing model in mice. At the doses of 200 and 400 mg/kg bodyweight, the extract showed significant anti-inflammatory activity in both models. At the samedoses, the extract also significantly reduced the number of acetic acid-induced abdominalconstriction (writhing) in mice. The crude extract also showed significant diuretic activity inalbino mice.