Effects of QZ-16 on blood glucose and lipids in Streptozotocin induceddiabetic rats > Volume 05 - 2005

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Oriental Pharmacy and Experimental Medicine
Volume 05 - 2005
Date: 2005

Journal: Pages 144-149

June 2005 | Effects of QZ-16 on blood glucose and lipids in Streptozotocin induceddiabetic rats…

Abul K Najmi1,*, KK Pillai1, Aftab Ahmad1 and M Aqil2

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Summary

​The present study was designed to investigate the hypoglycaemic and hypolipidaemic activitiesof Qurs-e-Ziabetus 16 (QZ-16) in Streptozotocin (STZ) induced diabetic rats. QZ-16, apolypharmaceutical herbomineral formulation developed on the principles of Unani medicine isused for non-insulin dependent diabetes mellitus (NIDDM). The elevated levels of fasting bloodglucose, serum levels of cholesterol, triglycerides and urea observed in rats treated with STZ (55mg/kg body wt.) were significantly reduced by the treatment of QZ-16 (240 mg/kg, p.o.) andgliclazide (30 mg/kg, p.o.). The reduced HDL cholesterol levels were also increased by the QZ-16and gliclazide treatments in the STZ induced diabetic rats. These data show that QZ-16 hashypoglycaemic, hypolipidaemic properties in STZ induced diabetic rats.


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