The phyto-oestrogens: its anticarcinogenic and antioxidant activity-a review > Volume 06 - 2006

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Oriental Pharmacy and Experimental Medicine
Volume 06 - 2006
Date: 2006

Journal: Pages 69-78

June 2006 | The phyto-oestrogens: its anticarcinogenic and antioxidant activity-a review…

Sitarina Widyarini1,* and Vivienne E Reeve2

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Summary

​The isoflavonoids comprise a group of phyto-oestrogens that have useful biological activitiesincluding oestrogenic, antioxidant and anticancer. As dietary components for humans, they arebioavailable from leguminous vegetables (such as genistein from soybean), and have been well-documented to have numerous health benefits. A wide range of epidemiological studies inhumans and limited studies in animals have identified isoflavonoids as potential chemopreventiveagents against hormone-dependent cancers. Therefore, an attempt has been made through thisreview to summarise the information in the mechanisms aspect of isoflavonoid phyto-oestrogensin inhibiting cancer in vitro and in vivo in the models of human cancers.


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