Antinociceptive activity of some Bangladeshi medicinal plant extracts > Volume 06 - 2006

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Oriental Pharmacy and Experimental Medicine
Volume 06 - 2006
Date: 2006

Journal: Pages 96-101

June 2006 | Antinociceptive activity of some Bangladeshi medicinal plant extracts…

SJ Uddin1,*, JA Shilpi1, R Rouf1, MM Ferdous2, L Nahar3 and SD Sarker4

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Summary

​The extracts of some Bangladeshi medicinal plants, Possur (Xylocarpus mekongensis), Dhundul(Xylocarpus granatum), Gab (Diospyros peregrina), Kadom (Anthocephalus chinensis) and Sundari(Heritiera fomes), were assessed for their possible antinociceptive activity using acetic acidinduced writhing model in mice. Most of these plants have been used in traditional medicine inBangladesh as well as in other countries for the treatment of various ailments ranging fromcommon cold to cancer. All these extracts significantly inhibited the acetic acid induced writhingin mice at the oral dose of 500 mg/kg body weight. The extract of Anthocephalus chinensis barkshowed the most potent writhing inhibition (69.47%, P < 0.001) and that of Diospyros peregrinabark had the least (33.54%, P < 0.02).


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