Chandanasav is an Ayurvedic preparation slightly reduced the gastrointestinal motility at the 15min time interval. It increased the latent period of castor oil induced diarrhoea, slightly decreasednumber of stool count and lowered the purging index values. Chandanasav significantly reducedthe onset and increased the duration of pentobarbital induced sleeping time. No significantanalgesic effect was observed from the hot plate study. Thus it may have mild constipating andcentral nervous system depressant activity without any effect on peripheral nervous system.