Phytochemical analysis of the antioxidant properties of Silybum marianum L > Volume 06 - 2006

본문 바로가기

사이트 내 전체검색

 » New Articles(2011~Present)
 » Articles (2001~2010)
      ∙ Volume 10 - 2010
      ∙ Volume 09 - 2009
      ∙ Volume 08 - 2008
      ∙ Volume 07 - 2007
      ∙ Volume 06 - 2006
      ∙ Volume 05 - 2005
      ∙ Volume 04 - 2004
      ∙ Volume 03 - 2003
      ∙ Volume 02 - 2002
      ∙ Volume 01 - 2001

Oriental Pharmacy and Experimental Medicine
Volume 06 - 2006
Date: 2006

Journal: Pages 167-173

September 2006 | Phytochemical analysis of the antioxidant properties of Silybum marianum L…

Barbara Pendry1, Kofi Busia2,* and Celia M Bell1



​A growing body of evidence supports lipid peroxidation as having a role in the pathogenesis ofliver disease. Although the probable cause of damage to human hepatocytes may be multifactorial, freeradicals have been implicated in a variety of liver diseases, particularly in the presence of ironoverload and toxic substances such as ethanol. Consequently, antioxidants, particularly those of plantorigin such as flavonoids, may help to reduce the risk of developing these diseases. Silybum (S.)marianum, a medicinal plant widely used in traditional European medicine for the treatment of liverdisorders, was evaluated for antioxidant activity. Thin layer chromatography and High PerformanceLiquid Chromatography analyses of crude extract of the plant confirmed the presence of a number offlavonoids reported in the literature. The antioxidant activity of these flavonoids was measuredthrough inhibition of lipid peroxidation and 1, 1-diphenyl-2- picrylhydrazyl radical scavenging. Thecrude plant extract showed marked antioxidant activity in both assays. These results suggest thatS. marianum contains flavonoids with antioxidant activity, capable of inhibiting or scavenging freeradicals, thus supporting its traditional use as a hepatoprotective agent.

This website Copyright (c) 2014 Institute of Korean Medicine Kyung Hee University All rights reserved.
Top View
Mobile View