Woodfordia fruticosa Kurz. (Lythraceae), commonly known as Dhayero, is used in the treatment ofvarious ailments in Nepal. In this study, the antioxidant capacity of crude extract and differentpolarity fractions of Woodfordia fruticosa flowers were assayed for their scavenging abilitiesagainst 1,1-diphenyl-2-picrylhydrazyl (DPPH) and nitric oxide radicals, competitive β-carotenebleaching, reducing power, metal chelating ability and total phenolic content. Crude extract andpolar fractions showed stronger antioxidant capacity and contained very high level of totalphenolics. They exhibited strong DPPH radical scavenging, nitric oxide scavenging and reducing power,medium β-carotene bleaching and poor metal chelating capacity. Positive correlation obtained betweentotal phenolic content and antioxidant capacity assays, indicated the contribution of phenolics towardsantioxidant capacity.