Protective effects of Polygala tenuifolia on ischemia-induced 4 vessel occlusionin rats > Volume 07 - 2007

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Oriental Pharmacy and Experimental Medicine
Volume 07 - 2007
Date: 2008

Journal: Pages 564-568

February 2008 | Protective effects of Polygala tenuifolia on ischemia-induced 4 vessel occlusionin rats…

Young-Ock Kim1, Su Kang Kim2, Ah-Rang Cho2,3 and Joo-Ho Chung2,*

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Summary

​The root of Polygala tenuifolia Willd (PT) is known to have neuroprotective effects and as anantidementic herb in Chinese and Japanese traditional medicine. We examined potentialneuroprotective effects of PT using the 4-vessel occlusion model in rats. In this study, the efficacyof PT for the prevention of neuronal damage and for the reduction of memory impairment wasinvestigated. The results indicate that PT confers significant neuroprotection especially forischemic hippocampal neurons.


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