In vitro anti-oxidant activity of the leaves of Dillenia indica > Volume 09 - 2009

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Oriental Pharmacy and Experimental Medicine
Volume 09 - 2009
Date: April 22, 2008

Journal: Pages 277-284

December 2009 | In vitro anti-oxidant activity of the leaves of Dillenia indica…

Moni Rani Saha1, Md Ashraful Alam1,*, SM Raquibul Hasan1, Raushanara Akter1, Md MokarramHossain1, Ehsanul Hoque Mazumder2 and Md Sohel Rana2

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Summary

​The methanol extract of Dillenia indica was tested for antioxidant activity as determined by free radicalscavenging of DPPH radical scavenging assay, reducing power, total antioxidant capacity measuredby phosphomolybdenum method, total phenolic content and total flavonoids content determinationassays. The extract showed significant activities in all antioxidant assays compared to the standardantioxidant in a dose dependent manner. In DPPH radical scavenging assay the IC50 value of theextract was found to be 100.53 µg/ml while ascorbic acid has the IC50 value 58.92 µg/ml. Dillenia indicaextract showed strong reducing power and total antioxidant capacity. Moreover, methanol extractsalso possess high amount of phenolics and flavovonoids and expressed as gallic acid and rutinequivalent respectively. The remarkable activities exhibited in reactive oxygen species scavengingmay attributed to the high amount of hydrophilic phenolics present in Dillenia indica.


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