Secondary metabolites (Triterpenes) from Couroupita guianensis > Volume 09 - 2009

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Oriental Pharmacy and Experimental Medicine
Volume 09 - 2009
Date: January 14, 2008

Journal: Pages 200-205

June 2009 | Secondary metabolites (Triterpenes) from Couroupita guianensis…

Rokeya Begum1,†, Mohammad S Rahman2, A M Sarwaruddin Chowdhury1, Choudhury M Hasan2and Mohammad A Rashid2,3,*

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Summary

​The n-hexane and carbon tetrachloride soluble fractions of a methanolic extract of the stem barkof the Couroupita guianensis furnished three compounds, identified as β-amyrin (1), betulin-3β-caffeate (2) and lupeol-3β-caffeate (3). The structures of the isolated compounds were deduced byextensive spectroscopic analysis as well as by comparison with published values. Compounds 1-3were subjected to antioxidant screening through free radical scavenging activity by DPPH (1,1-diphenyl-2-picrylhydrazyl), where compound 2 showed moderate antioxidant activity with IC50value 108.0 µg/ml.


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