Inhibitory effect of sakuranetin on (1,3)-β-glucan synthase > Volume 10 - 2010

본문 바로가기

사이트 내 전체검색


 » New Articles(2011~Present)
 » Articles (2001~2010)
      ∙ Volume 10 - 2010
      ∙ Volume 09 - 2009
      ∙ Volume 08 - 2008
      ∙ Volume 07 - 2007
      ∙ Volume 06 - 2006
      ∙ Volume 05 - 2005
      ∙ Volume 04 - 2004
      ∙ Volume 03 - 2003
      ∙ Volume 02 - 2002
      ∙ Volume 01 - 2001
 

Oriental Pharmacy and Experimental Medicine
Volume 10 - 2010
Date: July 07, 2009

Journal: Pages 44-49

March 2010 | Inhibitory effect of sakuranetin on (1,3)-β-glucan synthase…

Myung Ja You1, Bo MiKim1, Lok Ranjan Bhatt1, Kyu Yun Chai1,* and Seung Hwa Baek2,*

첨부파일

Summary

​An examination of the kinetic properties of UDP-glucose, (1,3)-β-glucans (callose) synthase, frommung bean seedlings (Sorbus commixta cortex) shows that these enzymes have a complex relationship withUDP-glucose and various effectors. Fluorescence assay showed that deoxynojirimycin increasedthe inhibitory effect of (1,3)-β-glucan synthase in a concentration-dependent manner. Theinhibitory effect of sakuranetin (34.34%) was higher than that of deoxynojirimycin (80.63%). Diskdiffusion method revealed that sakuranetin inhibited the growth of Candida albicans to a 1.5 mminhibition zone. These results suggest that sakuranetin, isolated from Sorbus commixta cortexextract, can be used as stable antifungal material.


This website Copyright (c) 2014 Institute of Korean Medicine Kyung Hee University All rights reserved.
Top View
Mobile View