Hepatoprotective and antioxidant activity of the methanolic extract ofMucuna pruriens Bak. roots > Volume 10 - 2010

본문 바로가기

사이트 내 전체검색


 » New Articles(2011~Present)
 » Articles (2001~2010)
      ∙ Volume 10 - 2010
      ∙ Volume 09 - 2009
      ∙ Volume 08 - 2008
      ∙ Volume 07 - 2007
      ∙ Volume 06 - 2006
      ∙ Volume 05 - 2005
      ∙ Volume 04 - 2004
      ∙ Volume 03 - 2003
      ∙ Volume 02 - 2002
      ∙ Volume 01 - 2001
 

Oriental Pharmacy and Experimental Medicine
Volume 10 - 2010
Date: June 30, 2010

Journal: Pages 79-85

June 2010 | Hepatoprotective and antioxidant activity of the methanolic extract ofMucuna pruriens Bak. roots…

M Mujeeb1,*, P Bagri1, V Aeri1 and SA Khan2

첨부파일

Summary

​The methanolic extract of natural roots of Mucuna pruriens was screened for hepatoprotective andantioxidant effects in carbon tetrachloride (CCl4) induced hepatotoxicity in Albino rats. Thedegree of protection was measured by estimating biochemical parameters like serum glutamateoxaloacetate transaminase, serum glutamate pyruvate transaminase, total protein and level ofserum bilirubin (both total and direct). The extract also reduced CCl4 induced lipid peroxidationboth in-vitro and in-vivo. Hepatoprotective activity of methanolic extract at dose 300 mg/kg bodyweight, i.p., was comparable with standard drug Silymarin (25 mg/kg, i.p.). Furthermore,histopathological experiments were also carried out to support the study.


This website Copyright (c) 2014 Institute of Korean Medicine Kyung Hee University All rights reserved.
Top View
Mobile View