Antimicrobial and lipid peroxidation inhibition activity of Oxystelmaesculentum (Asclepiadaceae) > Volume 10 - 2010

본문 바로가기

사이트 내 전체검색


 » New Articles(2011~Present)
 » Articles (2001~2010)
      ∙ Volume 10 - 2010
      ∙ Volume 09 - 2009
      ∙ Volume 08 - 2008
      ∙ Volume 07 - 2007
      ∙ Volume 06 - 2006
      ∙ Volume 05 - 2005
      ∙ Volume 04 - 2004
      ∙ Volume 03 - 2003
      ∙ Volume 02 - 2002
      ∙ Volume 01 - 2001
 

Oriental Pharmacy and Experimental Medicine
Volume 10 - 2010
Date: November 26, 2007

Journal: Pages 208-213

September 2010 | Antimicrobial and lipid peroxidation inhibition activity of Oxystelmaesculentum (Asclepiadaceae)…

Ashok Kumar D*, Thamil Selvan V, Prerona Saha, Aminul Islam, Upal Kanti Mazumder andMalaya Gupta

첨부파일

Summary

​The aerial parts of methanol extract of Oxystelma esculentum (MEOE) (Asclepiadaceae) was evaluated forin vitro lipid peroxidation and antimicrobial activity. Lipid peroxidation was assayed by thechange in optical density of the various concentrations (20 - 320 µg/ml) and the percentageinhibition was estimated. Ascorbate/FeSO4-induced peroxidation was inhibited by MEOE andstandard antioxidants such as BHA, BHT and the percentage inhibition of the methanol extractwas increased with dose dependent manner. The IC50 value of the MEOE, BHA and BHT for lipidperoxidation was found to be 135.24 µg/ml, 25.62 µg/ml and 17.13 µg/ml, respectively. Theantimicrobial activity of MEOE was determined by disc diffusion method with three gram-positive, five gram-negative and two fungal microorganisms. MEOE exhibited the antimicrobialactivity against the tested microorganisms except Salmonella typhimurium (MTCC 98). In presentstudy, it is concluded that MEOE has significant effect in the inhibition of lipid peroxidation andpossesses good antimicrobial activity.


This website Copyright (c) 2014 Institute of Korean Medicine Kyung Hee University All rights reserved.
Top View
Mobile View