Structure elucidation of a newly isolated saponin from Clerodendrumserratum (L) Moon > Volume 10 - 2010

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Oriental Pharmacy and Experimental Medicine
Volume 10 - 2010
Date: March 31, 2010

Journal: Pages 319-321

December 2010 | Structure elucidation of a newly isolated saponin from Clerodendrumserratum (L) Moon…

Santosh S. Bhujbal1,*, Rabindra K.Nanda1, Ramesh S.Deoda1, Dinesh Kumar1, Shailesh M.Kewatkar1, Laxmikant S.More1 and Manohar J.Patil2

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Summary

​Plant saponins are widely distributed amongst plants and have a wide range of biological properties.Icosahydropicenic acid, C51H80O19 ((4S,6bS)-8a-((4,5-dihydroxy-6-methyl-3-((3R)-3,4,5-trihydroxy-6-methyl-tetrahydro-2H-pyran-2-yloxy)-tetrahydro-2H–pyran–2-yloxy)carbonyl)-2-hydroxy-4, 6a,6b, 11, 14b-pentamethyl-11-(2-methylprop-1-enyl)-3-(3,4,5-trihydroxy-6-(hydroxymethyl) - tetrahydro-2H-pyran-2-yloxy)-1, 2, 3, 4, 4a, 5, 6, 6a, 6b, 7, 8, 8a, 9, 10, 11, 12, 12a, 14, 14a, 14b-icosahydropicene-4-carboxylic acid), a new saponin was first time isolated from the roots of Clerodendrum Serratum (L)Moon (Verbenaceae).The structure elucidation of the compound was carried out by 1H NMR andDART-MS studies.


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